From Homestar Runner Wiki
Mancuso is a person often mentioned in odd circumstances. In Biz Cas Fri 3, a Mancuso at Accounting is mentioned by Homestar Runner, who has on at least one occasion, put his Three-Hole-Punch in the microwave. In Where's an Egg, his garage is mentioned in the description. With a Flash decompiler, Mancuso appears to be the butler's name.
 Mancuso's Older Brother
Mancuso's Older Brother is the older brother of Mancuso. He was likely arrested at some point, due to an existent mugshot. According to his mugshot, he was born on May 28, 1976. In Costume Commercial, the announcer suggest wearing a reflector to prevent being accidentally run down Mancuso's Older Brother ever again, but also that it is possible that one will instead be intentionally run down by Mancuso's Older Brother.
- Debut: Costume Commercial