From Homestar Runner Wiki
Strong Bad has a noticable obsession with snakes.
- Email credit card — One of the things on "the_coolest_stuff_ever.com" is a two-headed cobra.
- Strong Bad's Character Video — One of Strong Bad's props is a wooden cut-out of Homestar Runner with a snake around his neck.
- Email flag day — The Strong Badia flag has a picture of a snake holding a knife in its tail. Also, Strong Bad makes a tattoo of said snake in Strong Mad's arm.
- Email dragon — Strong Bad says the "S" when he first makes the dragon is for "snake".
- RhinoFeeder — Some snakes slither up and down the screen during the game.
- A Folky Tale — Saddy Dumpington finds a weird snake and dresses like him in hopes of making the town depressed again.
- Teen Girl Squad Issue 7 — Tompkins asks, "Who wants to get hogtied, and pushed down, into, some snakewater?"
- Strong Bad is a Bad Guy — An Easter egg shows The Cheat's tattoo idea, "some kind of snake lady stabbing some kind of snake".
- Email myths & legends — One of Strong Badia's Seven Elemental Spirits is a snake holding a knife in its tail.
- Email alternate universe — When Strong Bad jumps through some panels in the Strong Badman comic, a lady is briefly seen riding a robot snake.
- Sketchbook from 14 Apr 2005 — Entitled "serpented!!", the Arrow'd Guy is sketched as a serpent.
- Email what I want — When Strong Bad describes the list of things he wants for Decemberween, he mentions a catapult that launches balls of cobras. In an Easter egg, the box for a board game called COBRA-PULT!! depicts a ball of cobras.
- Email fan club — In Strong Bad's fan fiction, he has Strong Sad being attacked by a sandwich-constrictor.
- Homestar Ruiner — Strong Bad fights snakes in the mini-game Snake Boxer 5.
- Strong Badia the Free Cave Girl Squad — Two snakes attack a girl who tries to write a love letter out of ancient pictographs.
- 8-Bit is Enough — Snake Boxer appears as a party member, and a pair of snakes are an obtainable item in the game.